Publications

Stress-related biomolecular condensates in plants

Scientific Year: 2023 DOI:10.1093/plcell/koad127

Authors: Jorge Solis-Miranda, Monika Chodasiewicz, Aleksandra Skirycz, Alisdair R Fernie, Panagiotis N Moschou, Peter V Bozhkov, Emilio Gutierrez-Beltran

The Plant Cell

biomolecular condensates
membraneless organelle
liquid-liquid phase separation

Protein interactome of 3′,5′-cAMP reveals its role in regulating the actin cytoskeleton

Scientific Year: 2023 DOI:10.1111/tpj.16313

Authors: Nicolas E Figueroa, Peter Franz, Marcin Luzarowski, Federico Martinez-Seidel, Juan C Moreno, Dorothee Childs, Aleksandra Ziemblicka, Arun Sampathkumar, Tonni Grube Andersen, Georgios Tsiavaliaris, Monika Chodasiewicz, Aleksandra Skirycz

The Plant Journal

protein interactors
3',5'-cAMP
metabolites
chemo-proteomics

Silencing translation with phenolic acids

Scientific Year: 2023 DOI:https://doi.org/10.1038/s41477-023-01497-8

Authors: Venkatesh P. Thirumalaikumar, Monika Chodasiewicz, Aleksandra Skirycz

Nature Plants

plant signalling
Plant stress responses

Involvement of small molecules and metabolites in regulation of biomolecular condensate properties

Scientific Year: 2023 DOI:10.1016/j.pbi.2023.102385

Authors: Israel Maruri-Lopez, Monika Chodasiewicz

Current Opinion in Plant Biology

biomolecular condensates
proteins
nucleic acids
small molecule complexes
liquid-liquid phase separation

Landscape of biomolecular condensates in heat stress responses

Scientific Year: 2022 DOI:10.3389/fpls.2022.1032045

Authors: Violeta Londono Velez, Fatema Alquraish, Ibrahim Tarbiyyah, Fareena Rafique, Duruo Mao, Monika Chodasiewicz

Frontiers in Plant Science

LLPS
biomolecular condensates
heat stress response
signaling
stress granules

2′,3′-cAMP treatment mimics the stress molecular response in Arabidopsis thaliana

Scientific Year: 2022 DOI:10.1093/plphys/kiac013

Authors: Monika Chodasiewicz, Olga Kerber, Michal Gorka, Juan C Moreno, Israel Maruri-Lopez, Romina I Minen, Arun Sampathkumar, Andrew D. L. Nelson, Aleksandra Skirycz

Plant Physiology

2',3'-cAMP
arabidopsis thaliana
stress response
RNA degradation

A New Approach to the Study of Plastidial Stress Granules: The Integrated Use of Arabidopsis thaliana and Chlamydomonas reinhardtii as Model Organisms

Scientific Year: 2022 DOI:10.3390/plants11111467

Authors: Fareena Rafique, Kyle J Lauersen, Monika Chodasiewicz, Nicolas E Figueroa

Plants

arabidopsis
chlamydomonas
abiotic stress
chloroplast
liquid-liquid phase seperation
stress granules
stress response

A manipulation of carotenoid metabolism influence biomass partitioning and fitness in tomato

Scientific Year: 2022 DOI:https://doi.org/10.1016/j.ymben.2022.01.004

Authors: Jianing Mi, Jose G Vallarino, Ivan Petrik, Ondrej Novak, Sandra M Correa, Monika Chodasiewicz, Michel Havaux, Manuel Rodriguez-Concepcion, Salim Al-Babili, Alisdair R Fernie, Aleksandra Skirycz, Juan C Moreno

Metabolic Engineering

abiotic stress
apocarotenoids
biomass and yield
carotenoids
metabolic engineering
metabolites and lipids
phytohormones

Affinity Purification Protocol Starting with a Small Molecule as Bait

Scientific Year: 2022 DOI:10.1007/978-1-0716-2624-5_2

Authors: Nicolas E Figueroa, Itzell E Hernandez-Sanchez, Israel Maruri-Lopez, Monika Chodasiewicz

Cell-Wide Identification of Metabolite-Protein Interactions 11-19, Methods in Molecular Biology Book

affinity purification
mass spectrometry
metabolites
ligand
protein-metabolite interactions
protein-protein interactions

Editorial: Biology of Stress Granules in Plants

Scientific Year: 2022 DOI:10.3389/fpls.2022.938654

Authors: Monika Chodasiewicz, J C Jang, Emilio Gutierrez-Beltran

Frontiers in Plant Science

stress granules
biology
eukaryotic organisms

Composition and function of stress granules and P-bodies in plants

Scientific Year: 2022 DOI:10.1016/j.semcdb.2022.11.008

Authors: Alyssa Kearly, Andrew D. L. Nelson, Aleksandra Skirycz, Monika Chodasiewicz

Seminars in Cell & Developmental Biology

biomolecular condensates
metabolites
P-bodies
proteins
stress granules
mRNA

A multi-OMICs approach sheds light on the higher yield phenotype and enhanced abiotic stress tolerance in tobacco lines expressing the carrot lycopene β-cyclase1 gene

Scientific Year: 2021 DOI:10.3389/fpls.2021.624365

Authors: Juan C Moreno, Silvia Martinez-Jaime, Monika Chodasiewicz, Ewelina Maria Sokolowska, Philipp Schulz, Axel Fischer, Urszula Luzarowska, Michel Havaux, Aleksandra Skirycz

Frontiers in Plant Science

Nicotiana tabacum cv Xanthi
ROS
abiotic stress
carotenoids
lycopene β-cyclase
omics
transcription factors
β-carotene

Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity

Scientific Year: 2021 DOI:10.1038/s42003-021-01684-3

Authors: Marcin Luzarowski, Ruben Vicente, Andrei Kiselev, Mateusz Wagner, Dennis Schlossarek, Alexander Erban, Leonardo Perez de Souza, Dorothee Childs, Izabela Wojciechowska, Urszula Luzarowska, Michal Gorka, Ewelina Maria Sokolowska, Monika Chodasiewicz, Juan C Moreno, Aleksandra Brzezinska, Bhavana Vegesna, Joachim Kopka, Alisdair R Fernie, Lothar Willmitzer, Jennifer C Ewald, Aleksandra Skirycz

Communications Biology

protein-metabolite interactions
saccharomyces cerevisiae
Ser-Leu dipeptide
phosphoglycerate kinase activity

Tyr-Asp inhibition of glyceraldehyde 3-phosphate dehydrogenase affects plant redox metabolism

Scientific Year: 2021 DOI:10.15252/embj.2020106800

Authors: Juan C Moreno, Bruno E Rojas, Ruben Vicente, Michal Gorka, Timon Matz, Monika Chodasiewicz, Juan S Peralta-Ariza, Youjun Zhang, Saleh Alseekh, Dorothee Childs, Marcin Luzarowski, Zoran Nikoloski, Raz Zarivach, Dirk Walther, Matias D Hartman, Carlos M Figueroa, Alberto A Iglesias, Alisdair R Fernie, Aleksandra Skirycz

arabidopsis
GAPDH
NADPH
central carbon metabolism
dipeptides

Plant Stress Granules: Trends and Beyond

Scientific Year: 2021 DOI:10.3389/fpls.2021.722643

Authors: Israel Maruri-Lopez, Nicolas E Figueroa, Itzell E Hernandez-Sanchez, Monika Chodasiewicz

Frontiers in Plant Science

stress granules
trends
dynamic membrane-less condensates
liquid-liquid phase seperation

The Isolation of Stress Granules from Plant Material

Scientific Year: 2020 DOI:https://doi.org/10.1002/cppb.20118

Authors: Monika Kosmacz, Aleksandra Skirycz

Current Protocols in Plant Biology

arabidopsis thaliana
affinity purification
plant metabolome
proteome
stress granules
stress granule extraction
stress response

Towards a functional understanding of the plant metabolome

Scientific Year: 2020 DOI:10.1016/j.pbi.2020.02.005

Authors: Monika Kosmacz, Ewelina Maria Sokolowska, Saad Bouzaa, Aleksandra Skirycz

Current Opinion in Plant Biology

plant metabolome
functional diversity

Identification and characterization of the heat-induced plastidial stress granules reveal new insight into Arabidopsis stress response

Scientific Year: 2020 DOI:10.3389/fpls.2020.595792

Authors: Monika Chodasiewicz, Ewelina Maria Sokolowska, Anna C Nelson-Dittrich, Aleksandra Masiuk, Juan C Moreno, Andrew D. L. Nelson, Aleksandra Skirycz

Frontiers in Plant Science

chlorophyll biosynthesis
metabolites
plastid
stress granules

Protein and metabolite composition of Arabidopsis stress granules

Scientific Year: 2019 DOI:10.1111/nph.15690

Authors: Monika Kosmacz, Michal Gorka, Stephan Schmidt, Marcin Luzarowski, Juan C Moreno, Jagoda Szlachetko, Ewa Leniak, Ewelina Maria Sokolowska, Kostika Sofroni, Arp Schnittger, Aleksandra Skirycz

New Phytologist

arabidopsis thaliana
CDKA1
affinity purification
stress granule extraction
stress granule metabolome
stress granule proteome
stress response

PROMIS, global analysis of PROtein-Metabolite Interactions using Size separation in Arabidopsis thaliana

Scientific Year: 2018 DOI:10.1074/jbc.RA118.003351

Authors: Daniel Veyel, Ewelina Maria Sokolowska, Juan C Moreno, Sylwia Kierszniowska, Justyna Cichon, Izabela Wojciechowska, Marcin Luzarowski, Monika Kosmacz, Jagoda Szlachetko, Michal Gorka, Michael Meret, Alexander Graf, Etienne H Meyer, Lothar Willmitzer, Aleksandra Skirycz

Journal of Biological Chemistry

chromatography
ligand-binding protein
metabolomics
protein-protein interactions
protein-small molecule interactions
proteomics
size-exclusion chromatography
systems biology

Low-oxygen response is triggered by an ATP-dependent shift in oleoyl-CoA in Arabidopsis thaliana

Scientific Year: 2018 DOI:10.1073/pnas.1809429115

Authors: Romy R. Schmidt, Martin Fulda, Melanie V. Paul, Max Anders, Frederic Plum, Daniel A. Weits, Monika Kosmacz, Tony R. Larson, Ian A. Graham, Gerrit T. S. Beemster, Francesco Licausi, Peter Geigenberger, Jos H. Schippers, Joost T. van Dongen

PNAS

low-oxygen response
ATP-dependent shift
oleoyl-CoA
arabidopsis

Interaction of 2’,3’-cAMP with Rbp47b plays a role in stress granule formation

Scientific Year: 2018 DOI:10.1104/pp.18.00285

Authors: Kosmacz M., Luzarowski M., Kerber O., Leniak E., Gutiérrez-Beltrán E., MorenoJ.C., Gorka M., Szlachetko J., Veyel D., Graf A., Skirycz A.

Plant Physiology

2',3'-cAMP
RNA degradation
stress granule formation
Rbp47b

Affinity purification with metabolomic and proteomic analysis unravels diverse roles of nucleoside diphosphate kinases

Scientific Year: 2017 DOI:10.1093/jxb/erx183

Authors: Marcin Luzarowski, Monika Kosmacz, Ewelina Maria Sokolowska, Weronika Jasinska, Lothar Willmitzer, Daniel Veyel, Aleksandra Skirycz

Journal of experimental botany

affinity purification
arabidopsis thaliana
NDPK
glutathionylation
metabolites
plant
protein-metabolite interactions
protein-protein interactions

System-wide detection of protein-small molecule complexes suggests extensive metabolite regulation in plants

Scientific Year: 2017 DOI:10.1038/srep42387

Authors: Daniel Veyel, Sylwia Kierszniowska, Monika Kosmacz, Ewelina Maria Sokolowska, Aenne Michaelis, Marcin Luzarowski, Jagoda Szlachetko, Lothar Willmitzer, Aleksandra Skirycz

Scientific Reports

small molecule complexes
metabolite regulation
protein detection

Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana

Scientific Year: 2015 DOI:10.1016/j.plantsci.2015.03.008

Authors: Liem T. Bui, Beatrice Giuntoli, Monika Kosmacz, Sandro Parlanti, Francesco Licausi

Plant Science

arabidopsis thaliana
ethylene response factor
hypoxia
transcriptional activation

Oxygen perception in plants

Scientific Year: 2014 DOI:10.1007/978-3-7091-1254-0_1

Authors: Monika Kosmacz, Daan A. Weits

Low oxygen stress in plants. Springer, Heidelberg.

oxygen
oxygen sensing

A trihelix DNA binding protein counterbalances hypoxia-responsive transcriptional activation in Arabidopsis

Scientific Year: 2014 DOI:10.1371/journal.pbio.1001950

Authors: Beatrice Giuntoli, Seung Cho Lee, Francesco Licausi, Monika Kosmacz, Teruko Oosumi, Joost T. van Dongen, Julia Bailey-Serres, Pierdomenico Perata

Plos Biology

trihelix DNA
binding protein
hypoxia
arabidopsis
transcriptional activation
ethylene-responsive
normoxia

Plant cysteine oxidases control the oxygen-dependent branch of the N-end rule pathway

Scientific Year: 2014 DOI:10.1038/ncomms4425

Authors: Daan A. Weits, Beatrice Giuntoli, Monika Kosmacz, Sandro Parlanti, Hans-Michael Hubberten, Heike Riegler, Rainer Hoefgen, Pierdomenico Perata, Joost T. van Dongen, Francesco Licausi

Nature communications

cysteine oxidases
N-end rule pathway
selective proteolysis

The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration

Scientific Year: 2014 DOI:10.1111/pce.12493

Authors: Monika Kosmacz, Sandro Parlanti, Markus Schwarzlander, Friedrich Kragler, Francesco Licausi, Joost T. van Dongen

Plant Cell and Environment

arabidopsis
ethylene response factor
N-end rule pathway
anoxia
confocal laser scanning microscopy
hypoxia
oxygen sensing

Missexpression of a Chloroplast Aspartyl Protease Leads to Severe Growth Defects and Alters Carbohydrate Metabolism in Arabidopsis

Scientific Year: 2012 ISSN:1237–1250 DOI:10.1104/pp.112.204016

Authors: Eleonora Paparelli, Silvia Gonzali, Sandro Parlanti, Giacomo Novi, Federico M. Giorgi, Francesco Licausi, Regina Feil, John E. Lunn, Henrike Brust, Joost T. van Dongen, Martin Steup, Pierdomenico Perata, Monika Kosmacz

Plant Physiology 160: 1237-1250

chloroplast
aspartyl
protease
growth defects
carbohydrate metabolism
arabidopsis

Oxygen sensing in plants is mediated by an N-end rule pathway for protein destabilization

Scientific Year: 2011 DOI:10.1038/nature10536

Authors: Francesco Licausi, Monika Kosmacz, Daan A. Weits, Beatrice Giuntoli, Federico M. Giorgi, Laurentius A. C. J. Voesenek, Pierdomenico Perata, Joost T. van Dongen

Nature 479, 419-422

oxygen sensing
N-end rule pathway
protein destabilization
eukaryotic organisms
respiratory energy production

Navigating biomolecular condensates in plants from patterns to functions

Scientific Year: 2024 DOI:10.1016/j.molp.2024.08.001

Authors: Yansong Miao, Monika Chodasiewicz, Xiaofeng Fang

Molecular plant,

also available on Science direct

https://www.sciencedirect.com/science/article/pii/S1674205224002569

https://doi.org/10.1016/j.molp.2024.08.001

Engineering a One Health Super Wheat

Scientific Year: 2024 DOI:https://doi.org/10.1146/annurev-phyto-121423-042128

Authors: Francisco M. Ayala, Itzell E Hernandez-Sanchez, Monika Chodasiewicz, Brande B.H. Wulff, Radim Svačina

Annual Review of Phytopathology

wheat
Triticum aestivum
disease resistance
stress tolerance
genetic modification
GM crops